July 2013

CLAO E-NEWS July 2013: 
IN THIS ISSUE

  • CLAO INTERNATIONAL SYMPOSIUM & CONGRESS 2014
  • SJOGREN's SYNDROME TEST 
  • INCREASED COSTS OF VISION RELATED DISEASES
  • NEW CORNEAL LAYER REPORTED
  • CLAO EDUCATIONAL PROGRAMS AT THE AAO
  • CONTACT LENS GIVES TELESCOPIC VISION
  • EUROPEAN CONTACT LENS SOCIETY ANNUAL MEETING
  • PRODUCT & INDUSTRY NEWS
  • MARK YOUR CALENDAR
  • CLAO "DID YOU KNOW?

CLAO International Symposium & Congress 2014

CLAO announces its next meeting will be a major international meeting to be held June 12 - 15, 2014 in Toronto,
Canada. Programming is being developed by Dr. Debbie Jacobs, Scientific Programs Chair,along with the CLAO Scientific Programs Committee. Clinicians and researchers in the fields of contact
lens, anterior segment, and ocular surface disease from the United States, Canada, and around the world will be presenting the latest advances. Topics covered will include:

  • What's New for Keratoconus 
    • Corneal Collagen Crosslinking: International Update
    • Specialty Soft Lenses and Hybrid Lenses
    • Scleral RGP Lenses
  • Orthokeratology: Threat or Opportunity?
  • Aspherics, Wavefront-Optimized Contact Lenses, and  Wavefront-Guided Contact Lenses 
  • Choosing an IOL: Imaging, Optics, Visual Acuity and Visual Function
  • Contact Lens as Part of Your Practice: Business Aspects of  Prescribing and Dispensing
  • Risk Management/Ethics
  • Contact Lens as a Therapeutic Platform 
    • Drug Delivery
    • Myopia Control
  • Contact Lens Discomfort: New Options, New Directions

Additional information will be available soon at www.clao.org.

Sjogren's Syndrome Test

"Nicox (Sophia Antipolis, France) has gained exclusive U.S. rights to a lab test targeted at early detection and diagnosis of Sjogren's syndrome. Nicox will be responsible for all marketing activities, while test developer Immco will carry out the test in its CLIA-approved laboratory in Buffalo, N.Y., and be responsible for regulatory activities and reimbursement, Nicox said in a press release. Nicox also has a nine-month option to negotiate an agreement to promote the test in the rest of the world. The test is based on the discovery of novel antibodies in Sjogren's syndrome: SP-1 (salivary
gland protein-1), CA-6 (carbonic anhydrase-6), and PSP (parotid secretory protein). Traditional tests use ANA, Ro, La and RF antibodies that are associated with later-stage disease, Nicox said. The novel antibodies were found in 45% of patients meeting the criteria for Sjogren's syndrome who lacked the traditional antibodies for Ro or La. In patients diagnosed with idiopathic xerostomia and
xerophthalmia for less than two years, 76% had antibodies to SP-1 and/or CA-6 while only 31% had antibodies to Ro or La." (This quote was from the June 21,2013 issue of EyeWorld Weely Update.)

Increased Costs of Vision Related Diseases

Prevent Blindness America has issued a report that the "total economic burden of eye disorders and vision loss in the United States this year" will be $139 Billion. This is far greater than previous data had indicated." A breakdown of estimated costs of eye disorders and vision loss from the perspective of three payers: government ($47.4 billion), private insurance ($20.8 billion in direct
medical costs and $1.3 billion for long term care) and patients and their families ($71.6 billion)." To view the full report, please click here.

New Corneal Layer Reported

In an article in press of the journal Ophthalmology, a new corneal layer is reported on and referred to as "Dua's Layer" in recognition of Dr. Harminder Dua, the lead researcher of the study group at the University of Nottingham that submitted the paper. They report a distinct layer that occurs between the corneal stroma and Descemet's membrane (making it the fourth layer from the
front). This layer is acellular, measuring only 15µ thick (0.00059 inches) and "despite its thinness, the layer is very strong and impervious to air." It is composed of 5 to 8 lamellae of predominantly type-1 collagen bundles arranged in transverse, longitudinal, and oblique directions. The

researchers indicate their finding will have considerable impact on posterior corneal surgery possibly helping improve outcomes for corneal graft and implants specifically as well as advance the understanding of corneal biomechanics and posterior corneal pathology such as acute hydrops, Descematocele and pre-Descemet's dystrophies. For additional information please click here.

Contact Lens Gives Telescopic Vision

Mark Ward, Technology correspondent at BBC News reported that "Researchers have created contact lenses which, when paired with special spectacles, bestow telescopic vision on their wearers. The contact-lens-and-spectacles combination magnifies scene details by 2.8 times. Polarizing filters in the spectacles allow wearers to switch between normal and telescopic vision. The telescopic sight system has been developed to help people suffering age-related blindness.
Age-related macular degeneration is one of the most common forms of blindness and damages the part of the eye, the macula, that handles fine detail. As this area degenerates, sufferers lose the ability to recognize faces and perform tasks, such as driving and reading, that rely on picking up details."
"The contact lens created by the researchers has a central region that lets light through for normal vision. The telescopic element sits in a ring around this central region. Tiny aluminum mirrors scored with a specific pattern act as a magnifier as they bounce the light around four times within
the ring before directing it towards the retina. In ordinary use, the magnified image is not seen as it is blocked by polarizing filters set in a companion pair of spectacles. Wearers can switch it on by changing the filters on the spectacles so the only light falling on their retina comes from the magnified stream.
For their filtering system, the researchers, led by Joseph Ford at UC San Diego and Eric Tremblay at Switzerland's EPFL, adapted a pair of glasses that Samsung produces for some of its 3D TV sets. In normal use, these spectacles create a 3D effect by alternately blocking the right or left lens. The prototype contact lens produced by the team is 8mm in diameter, 1mm thick at its centre and
1.17mm thick in its magnifying ring. "The most difficult part of the project was making the lens breathable," Dr Tremblay told the BBC. "If you want to wear the lens for more
than 30 minutes you need to make it breathable."
"The contact lenses might find a role on the battlefield to help soldiers.
Gases have to be able to penetrate the lens to keep the parts of the eye covered by the contact, especially the cornea, supplied with oxygen," he said. The team has solved this problem by
producing lenses riddled with tiny channels that let oxygen flow through. However, said Dr
Tremblay, this made manufacturing the lenses much more difficult. "The fabrication tolerances are quite challenging because everything has to be so precise."
"Despite this, gas-permeable versions of the telescopic lens are being prepared that will be used in clinical trials in November, he said. Eventually it should be possible for those with age-related sight problems to wear the telescopic lenses all day. The lenses are an improvement on other ways these sight problems have been tackled which has included surgery to implant a telescopic lens or
wearing bulky spectacles that have telescopic lenses forming part of the main lens.
"Clara Eaglen, eye health campaigns manager at the RNIB said the research looked "interesting" and praised its focus on macular degeneration. "It is encouraging that innovative products such as these telescopic contact lenses are being developed, especially as they aim to make the most of a person's existing vision," she said. ""Anything that helps to maximize functioning vision is very important as this helps people with sight loss to regain some independence and get out and about again, helping to reduce isolation."

"The lenses may one day find their way into other areas as the research was being funded by Darpa, the research arm of the US military. "They are not so concerned about macular degeneration," he said. "They are concerned with super vision which is a much harder problem. "That's because the standard is much higher if you are trying to improve vision rather than helping someone whose eyesight has deteriorated," he said."

CLAO Educational Programs at AAO

CLAO will be hosting the following educational programs at the 2013 American Academy of Ophthalmology Annual Meeting in New Orleans: A 90-minute Symposium, a two-hour Skills Transfer Course and a Didactic Course on contact lenses in the ophthalmology practice. For information on the AAO Program visit their meeting website.

European Contact Lens Society Annual Meeting

The European Contact Lens Society of Ophthalmologists (ECLSO) will be holding its annual meeting

October 25- 27, 2013 in Munich, Germany. CLAO Board Members Bruce R. Koffler, MD and Deborah S. Jacobs, MD will be presenting at the meeting. For program and registration information, visit www.eclso.eu.

Product & Industry News

I nform ation in this section has been provided to CLAO by press releases, online sources and other m eans. CLAO does not w arranty its accuracy; nor does notice of a product in this section

constitute an endorsem ent by CLAO.

Alcon has introduced into the US their "CibaVision DAILIES TOTAL 1." The company refers to this product as "Water Gradient Contact Lenses." The lens is a 33% water, high-Dk silicone lens for daily replacement. The company indicates that the surface of the lens is approximately 80% water while the matrix on the inside remains low water (thus providing high Dk). The lens surface provides for initial comfort upon lens placement on the eye as well as long term comfort through the day. For more information on the product visit http://www.dailies.com/.

In other news the company has sponsored a digital supplement by Contact Lens Spectrum on their
Clear Care Cleaning and Disinfecting Solution, a hydrogen peroxide contact lens care system entitled "A Clear Advantage." To view this supplement, please click here.

Bausch and Lomb, Inc., has sponsored a digital supplement by Contact Lens Spectrum on its PureVision2 contact lenses entitled "The Impact and Importance of Clear, Crisp Vision on Patient Satisfaction." To view this supplement visit: http://www.visioncareprofessional.com/digital/bl/5/index.html

CooperVision Inc., is supporting a consumer promotion to celebrate summer with its #no2views social media photo contest. During four weeks, which began July 8, CooperVision will announce a new summer theme on its Facebook page every Monday. Participants have only to post an image or photograph on Instagram that best describes their unique view of the theme and include the hashtag #no2views. Fans can vote for their favorite image via CooperVision's Facebook page, and the entry with the most "likes" will win one of four weekly prizes including a movie night package, digital camera, professional photo shoot or $500 shopping spree, plus where applicable a six-month supply of CooperVision contact lenses. At the end of the contest, the four weekly winners will be posted on CooperVision's Facebook page, and the fans will vote for the most unique image overall. The grand prize winner will receive an iPad with Retina Display and where applicable a year's supply of CooperVision contact lenses. The #no2views contest will run from July 8, 2013, to August 12,

2013, with winners announced Mondays, July 15, 22, 29, August 5, and the Grand Prize winner announced on August 12. For more information, visit the CooperVision Facebook Page. Oasis Medical has entered into a joint venture with Shape Ophthalmics (Denver, Colo.) to introduce a proprietary shape memory plug technology triggered by natural body heat. Oasis

Medical will be the sole manufacturer of the punctal plug for the treatment of dry eye, the company said. Distribution is expected to begin in 2014. (Reported in EyeWorld Weekly Update, June 28,
2013)

The U.S. Environmental Protection Agency (EPA) is working to educate patients in regard to contact lens safety and care. On the EPA website is a document entitled, "Do You Wear Contact Lenses? - There's Something You Should Know..." It covers information on Acanthamoeba based on data from the Centers for Disease Control (CDC). To view this document (it is in easy to read question and answer format) visit http://water.epa.gov/action/advisories/acanthamoeba/index.cfm

The U.S. Food and Drug Administration is urging ophthalmologists to report occurrences of adverse patient reactions caused by decorative contact lenses to its MedWatch program. The FDA is emphasizing the need to report adverse reactions, especially if the lenses were purchased without a prescription, as the agency can only take action against illegal sellers when violations are reported. Consumers can report decorative lens-related problems directly to their local FDA Consumer Complaint Coordinator.

Vistakon, Johnson & Johnson Vision Care, Inc., has introduced 1-Day Acuvue TruEye (narafilcon A) contact lenses, a silicone hydrogel daily disposable lens, in the U.S., the company announced. These lenses will "gradually replace" the TruEye (narafilcon B) line launched in the U.S. in 2010. In other news, the company has developed Healthy Vision & Contact Lenses, an educational resource for in-office, website, and social media use. Healthy Vision & Contact Lenses offers helpful "Do's and Don'ts" for handling and wearing contact lenses and offers some easy-to- follow steps on how to reduce the risk of contact lens-related infection through proper use and care of lenses as well as lens-care products such as contact lens cases. It also includes a section for eyecare professionals and/or staff to fill out with patients to reinforce replacement schedules,

proper cleaning and disinfecting techniques, and a reminder on when to change their contact lens case. Information about other resources where consumers can find helpful information about proper wear and care is also included. The educational piece is not brand specific. Healthy Vision & Contact
Lenses is available in both PDF and print versions. The PDF copies, which practitioners can
customize/personalize to include their contact information can be viewed and downloaded at www.ACUVUEProfessional.com/HVCL . The print versions include 50 tear-sheets on a pad. To request a pad, send your name and address to healthyvision@its.jnj.com.

Mark Your Calendar

The European Contact Lens Society of Ophthalmologists (ECLSO)

will be holding its annual meeting October 25- 27, 2013 in Munich, Germany. For more information, visit www.eclso.eu.

The 2013 American Academy of Ophthalmology (AAO) Annual Meeting is scheduled for November 15-19, in New Orleans, LA. JCAHPO holds its annual ACE meeting in conjunction with the AAO. For more information, visit www.aao.org

The American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting is scheduled for April 25-29, 2014 in Boston, MA. For more information visit www.ascrs.org.

The CLAO International Symposium & Congress is being planned by the CLAO Scientific Programs Committee to be held June 12 - 15, 2014 in Toronto, Canada. Information on this meeting will soon be available on the CLAO website at www.clao.org.

CLAO "Did You Know?"

Did you know that CLAO has two websites on the internet, one designed for members at www.clao.org and one designed for the public at www.ContactLensDocs.com and that both have been recently redesigned and updated for ease of use?

Contact Lens Event Reporting:

To report adverse contact lens reactions, visit the website or call (800) FDA-1088.
To report possible grievances related to the Fairness to Contact Lens Consumers Act or the associated Contact Lens Rule, click here.

Contact CLAO:

CLAO, 4000 Legato Road #700, Fairfax, VA. 22033
Phone: 855-264-8818 Fax: 703-434-3003 Email: eyes@clao.org
Web: www.clao.org, and www.ContactLensDocs.com